Oxford Nanopore Technologies on cord

Oxford Nanopore Technologies

Applications Bioinformatician

External position
Oxford, UK
Hiring internally for Oxford Nanopore Technologies?
BioTech · MedTech
Our goal is to enable the analysis of anything, by anyone, anywhere.
Posted
3 weeks ago
Checked
cord regularly checks that external positions are still open
2 days ago

Skills & Experience

Job roles: AI Engineer
Experience level: Mid, Senior
Core skills considered: Python, R, Git
Other skills considered: Cloud Computing, AWS, Data Analysis

Logistics

Base salary: Undisclosed
Some companies on cord are unable to disclose salaries publicly due to internal company policies. Message the company for salary information.
Employment type: Permanent
Remote working: Hybrid (up to 3 remote days p/w)
Visa sponsorship: Not available

Job Description

The Proof of Concept Clinical Applications team works within R&D to evaluate the feasibility of novel applications of Oxford Nanopore sequencing examining human disease, with a particular focus on rare disease.

As a member of the Proof of Concept Clinical Applications team, the successful candidate will primarily interpret sequencing data generated by lab scientists within the team, in a range of biological contexts aiming to showcase the abilities of the technology and develop proof of concept workflows to fill market niches. You should also be prepared to work with others across the wider Applications group to share expertise and collaborate where appropriate and to communicate your findings to internal stakeholders through presentations, reports and discussions in meetings.

As this role is within a multi-disciplinary team, the position is offered as hybrid, with an expectation of being in the Oxford office at least two days a week.


Responsibilities

  • Initial investigations of sequencing data to identify the potential of an experimental design.
  • Performing evaluation of appropriate bioinformatics tools for a given application, and carrying out defined custom analysis where needed.
  • Independently deliver assigned analysis tasks while escalating priorities, design decisions and blockers.
  • Support evaluation and development of defined proof-of-concept analyses; seek guidance on analysis design, interpretation and roadblocks.
  • Developing initial proof-of-concept pipelines for analysis of DNA, cDNA and direct RNA sequencing data using ONT's nanopore sensing platform, with regular guidance from a senior bioinformatician/manager, including task prioritization and mentoring.
  • Working collaboratively with laboratory-based scientists in the group to contribute suggestions on experimental design, to interpret the data generated in the appropriate biological context, and to report the results clearly.
  • Working with the team to make analysis and figure contributions to conference talks and posters.
  • Working closely with other applications groups in different locations to keep up-to-date with the latest developments, provide feedback and incorporate them into analyses where appropriate.

What you'll bring

To be successful you'll have an MSc or equivalent experience, involving analysis and visualization of DNA and RNA sequence data, plus an undergraduate degree in a Biological Science or Computer Science. Additionally, having a PhD or job experience in a relevant field would be beneficial.

We'll expect you to have a track record of successfully performing appropriate bioinformatics sequence analyses for at least a couple of research projects and awareness of the whole experimental process, from the initial experimental concept to biologically meaningful results. In addition, you'll have some practical experience of handling and analysing large human datasets, ideally in a clinical research setting. An awareness of the concepts of assembly, phasing and variant calling, and how to perform them would be beneficial. You would be working closely with lab scientists to continually refine the experimental and analytical approaches. Therefore, the role is a mixture of collaboration for project design and independent analysis, though the bioinformatics will be supported as appropriate. An important part of the role is also keeping up to date with advances in genetics and genomics.


Specific technical experience that would be expected for the role:

  • Programming experience (python, R)
  • Graphical visualisation experience
  • Experience of using a terminal interface, HPC and scheduling
  • Familiarity with common bioinformatics file formats
  • Experience with common bioinformatic tools (e.g. samtools, bedtools, IGV)
  • Package management (conda)
  • Version control (git, Github/Gitlab)

Specific technical experience that would be beneficial for the role:

  • Experience with Oxford Nanopore sequencing data
  • Experience with human clinical data regulations
  • Experience with assembly, phasing and/or variant calling
  • Claude or Codex experience
  • Workflow management systems (nextflow, snakemake)
  • Cloud usage (AWS EC2 and s3)
  • Statistics

You're also someone with good communication and interpersonal skills with an enthusiasm for technology. You feel confident discussing and presenting data within the team and with other colleagues. You are versatile, have excellent problem-solving and time management skills and the ability to work on multiple projects simultaneously. It will be important to be able to work efficiently both independently, supported by regular check-ins, and as part of a team.

This role will suit a curious, organized individual with the ability to adapt based on changing business needs and looking for a supportive environment in which to further develop their skills.

Company Benefits

We offer outstanding benefits to include an attractive bonus, generous pension contributions, private healthcare and an excellent starting salary. Based within beautiful, landscaped surroundings with tree-lined walks, water features and a lake, all of which make for a wonderful working environment.
Applications Bioinformatician at Oxford Nanopore Technologies
Position posted 3 weeks ago

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Starling Bank on cord

Starling Bank

Full Stack Engineer (ML Ops)

London, UK
FinTech · Banking · Finance
A better bank for everyone
Active
over 6 months ago
Responds to
0% of requests
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1h 55m
Requests
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Skills & Experience

Job roles: Full Stack
Experience level: Mid, Senior
Core skills considered: Java, React, Redux, AWS, JavaScript

Logistics

Base salary: £70K - £110K
Employment type: Permanent
Remote working: Hybrid (up to 2 remote days p/w)
Visa sponsorship: Not available

Job Description

Starling is the UK’s first and leading digital bank on a mission to fix banking! Our vision is fast technology, fair service, and honest values. All at the tap of a phone, all the time.

Starling is the UK’s first and leading digital bank on a mission to fix banking! We built a new kind of bank because we knew technology had the power to help people save, spend and manage their money in a new and transformative way.

We’re a fully licensed UK bank with the culture and spirit of a fast-moving, disruptive tech company. We’re a bank, but better: fairer, easier to use and designed to demystify money for everyone. We employ more than 3,000 people across our London, Southampton, Cardiff and Manchester offices.

Our technologists are at the very heart of Starling and enjoy working in a fast-paced environment that is all about building things, creating new stuff, and disruptive technology that keeps us on the cutting edge of fintech. We operate a flat structure to empower you to make decisions regardless of what your primary responsibilities may be, innovation and collaboration will be at the core of everything you do. Help is never far away in our open culture, you will find support in your team and from across the business, we are in this together!

The way to thrive and shine within Starling is to be a self-driven individual and be able to take full ownership of everything around you: From building things, designing, discovering, to sharing knowledge with your colleagues and making sure all processes are efficient and productive to deliver the best possible results for our customers. Our purpose is underpinned by five Starling values: Listen, Keep It Simple, Do The Right Thing, Own It, and Aim For Greatness.

Hybrid Working

We have a Hybrid approach to working here at Starling - our preference is that you're located within a commutable distance of one of our offices so that we're able to interact and collaborate in person. We don't like to mandate how much you visit the office and work from home, that's to be agreed upon between you and your manager.

Our Data Environment

Our Data teams are excited about the value of data within the business, powers our product decisions to improve things for our customers and enhance effective and agile decision making, regardless of what their primary tech stack may be. Hear from the team in our latest blogs or our case studies with Women in Tech.

We are looking for talented data professionals at all levels to join the team. We value people being engaged and caring about customers, caring about the code they write and the contribution they make to Starling. People with a broad ability to apply themselves to a multitude of problems and challenges, who can work across teams do great things here at Starling, to continue changing banking for good.

Requirements

We have built our entire banking platform in house and mostly in Java. We are looking for people who want to work on building the tooling that is used by our engineers on a daily basis.

We are looking for people who are truly full stack, and are as comfortable polishing their javascript front end as they are debugging the innards of their java applications database interactions, or standing up infrastructure with terraform. We are looking for people who can:

  • Design REST apis.
  • Code backend services, ideally using Java, or another other server side compiled language.
  • Develop modern front ends, ideally using React and Redux.
  • Get their code into the cloud and support it there, ideally on AWS.
  • Believe in clean coding, simple solutions, automated testing and continuous deployment.
  • Like to take ownership of a feature from the original idea through to live.
  • Think (like us) that a small number of empowered developers is the right way to deliver software.

Company Benefits

  • 33 days holiday (including flexible bank holidays)
  • An extra day’s holiday for your birthday
  • 16 hours paid volunteering time a year
  • Part-time and/or flexible hours available for most roles
  • Salary sacrifice, company enhanced pension scheme
  • Life insurance at 4x your salary
  • Hybrid/remote working
  • Private Medical Insurance with VitalityHealth including mental health support and cancer care. Partner benefits include discounts with Waitrose, Mr&Mrs Smith and Peloton
  • Generous family-friendly policies
  • Varied social groups set up and run by our employees
  • Perkbox membership giving access to retail discounts, a wellness platform for physical and mental health, and weekly free and boosted perks
  • Access to initiatives like Cycle to Work, Salary Sacrificed Gym partnerships and Electric Vehicle (EV) leasing

Full details are available on our careers site

Interview Process

Interviewing is a two way process and we want you to have the time and opportunity to get to know us, as much as we are getting to know you! Our interviews are conversational and we want to get the best from you, so come with questions and be curious. In general you can expect the below, following a chat with one of our Talent Team:

  • Stage 1 - 30 mins with one of the team
  • Stage 2 - Take home challenge
  • Stage 3 - 90 mins technical interview with two team members
  • Stage 3 - 45 min final with an executive and a member of the people team
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